论文部分内容阅读
目的:探讨埃索美拉唑和伊托必利联合用药治疗反流性食管炎的临床疗效。方法:选择2008—2010年间来我院就诊的反流性食管炎的病人,随即分为三组,实验组用埃索美拉唑和伊托必利联合给药治疗,另外两组分别单独用埃索美拉唑或伊托必利,作为对照组。观察各组病人治疗效果并进行疗效评价。结果:实验组和单独给药的对照组显效率分别为61.1%、22.2%和27.8%,总体有效率分别为100%、83.3%和77.8%,差别具有统计学意义,P<0.05。结论:埃索美拉唑和伊托必利联合治疗反流性食管炎效果优于单独用药。
Objective: To investigate the clinical efficacy of combination of esomeprazole and itopride in the treatment of reflux esophagitis. Methods: The patients with reflux esophagitis treated in our hospital from 2008 to 2010 were randomly divided into three groups. The experimental group was treated with esomeprazole and itopride. The other two groups were used alone Esomeprazole or Itopride as a control group. Observed the treatment effect of each group of patients and evaluated the efficacy. Results: The effective rates of the experimental group and the control group were 61.1%, 22.2% and 27.8%, respectively. The overall effective rates were 100%, 83.3% and 77.8% respectively. The difference was statistically significant (P <0.05). Conclusions: The combination of esomeprazole and itopride is superior to reflux alone in the treatment of reflux esophagitis.