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目的探讨胸膜外孤立性纤维瘤(ESFT)影像学表现及其病理学特征。方法回顾性分析6例经病理证实的ESFT的CT和MRI表现,并将影像学表现与病理组织学和免疫组化结果相对照。结果 ESFT发生在小脑、食管、眼眶、盆腔各1例,后腹膜2例。CT表现为圆形或卵圆形肿块,边界较清楚,3例密度均匀,2例密度不均匀。MRI表现为T1WI呈低或等信号,T2WI呈高、低混杂信号。增强后肿瘤呈“渐进性”及“地图样”强化。病理学检查肿瘤细胞呈梭形、卵圆形、圆形,免疫组化CD34及Vimentin均表达阳性。结论 ESFT是一种少见的间叶源性软组织肿瘤,影像学表现不典型,确诊需靠病理学及免疫组化检查。
Objective To investigate the imaging features and pathological features of extrapleural solitary fibroma (ESFT). Methods The CT and MRI manifestations of 6 pathologically confirmed ESFTs were retrospectively analyzed. The imaging findings were compared with the histopathological and immunohistochemical results. ESFT occurred in the cerebellum, esophagus, orbit, pelvic in 1 case, retroperitoneal in 2 cases. CT showed round or oval tumor, the border is more clear, 3 cases of uniform density, 2 cases of uneven density. MRI showed low or equal signal on T1WI, high and low signal on T2WI. Enhanced tumor was “progressive” and “map” to strengthen. Pathological examination of tumor cells was spindle, oval, round, immunohistochemical expression of CD34 and Vimentin were positive. Conclusion ESFT is an uncommon mesenchymal soft tissue tumor. The imaging findings are not typical. ESFT depends on pathology and immunohistochemistry.