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作者报道50例肺癌手术切除标本,组织学呈非感染性变化者42例、内有9例示有感染。这与公认的阻塞性局限性肺炎是由感染所致的观点不同。结果50例中周围型肺癌28例、中心型16例、混合型6例。组织分类鳞癌21例、腺癌25例、大细胞癌3例、腺鳞癌1例。15例标本大体和组织学改变分为6类:①支气管扩张和(或)细支气管扩张;②肺泡内积液;③间质性肺炎并有肺泡内含脂质积聚的巨噬细胞;④肺间质纤维化;⑤急性支气管炎或细支气管炎;⑥伴有机化肺炎的闭塞性细支气管炎,均列为非感染性改变。50例中21例气道异常为非感染性,表现为粘液栓塞的支气管扩张和(或)细支气管扩张,气道壁有淋巴细胞浸润而无中性粒细胞和坏死。肺实质改变50例中有42例为非感染性,表现为主气道阻塞,占肺叶或肺段大部,常见肿瘤阻塞小支气管和细支气管,并可见阻塞性肺炎的3个不同阶段:①肺泡内积液;②间质性肺炎伴肺泡(?)泡沫巨噬细胞聚集(内生脂质性肺
The authors report 50 cases of lung cancer resection specimens, histologically non-infectious changes in 42 cases, 9 cases showed infection. This is in contrast with the accepted view that obstructive PSV is caused by an infection. Results Among 50 cases, there were 28 cases of peripheral lung cancer, 16 cases of central type and 6 cases of mixed type. Tissue classification of squamous cell carcinoma in 21 cases, adenocarcinoma in 25 cases, large cell carcinoma in 3 cases, adenosquamous carcinoma in 1 case. 15 cases of gross and histological changes were divided into six categories: ① bronchiectasis and (or) bronchiectasis; ② alveolar effusion; ③ interstitial pneumonia and alveolar lipid accumulation in macrophages; ④ lung Interstitial fibrosis; ⑤ acute bronchitis or bronchiolitis; ⑥ obliterative bronchiolitis associated with organic pneumonia, were classified as non-infectious changes. Twenty-one of the 50 patients had abnormal airway infections that were noninfectious, manifested as bronchiectasis and / or bronchiectasis of mucosal embolism with infiltration of lymphocytes in the airway wall without neutrophils and necrosis. Forty-two of the 50 cases of lung changes were noninfectious, showing obstruction of the main airway, accounting for most of the lobes or lung segments. The common tumors obstructed the bronchus and bronchioles and showed three stages of obstructive pneumonia: ① Alveolar effusion; interstitial pneumonia with alveolar (?) Foam macrophage aggregation (endogenous lipoidal lung