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扩张型心肌病是由于心功能不全而出现症状及体征的原因不明的疾病。某些因素包括酒精、营养缺乏、产后及病毒感染都已被归为心肌病的病因。一种潜在性免疫功能紊乱也曾提示为一种与出现心内膜纤维化及少量淋巴细胞或其他单核细胞浸润有关的发病机理。本文估价了扩张型心肌病患者中某些体液及细胞免疫参数,旨在研究一种可能参与该病发病机理的潜在性免疫失调。方法:18个月中共观察了36例患者。21例(男14例,女7例,年龄自17～58岁)有充血性心力衰竭而不伴有冠状动脉病变、家族性心肌病、风湿热病
Dilated cardiomyopathy is a known cause of symptoms and signs due to cardiac insufficiency. Some factors, including alcohol, nutritional deficiencies, postpartum and viral infections have all been attributed to the etiology of cardiomyopathy. A potential immune dysfunction has also been suggested as a pathogenesis associated with the development of endocardial fibrosis and the presence of small numbers of lymphocytes or other mononuclear cells. This article assesses some of the humoral and cellular immune parameters in patients with dilated cardiomyopathy and aims to investigate a potential immune disorder that may be involved in the pathogenesis of the disease. Methods: A total of 36 patients were observed at 18 months. Twenty-one patients (14 males and 7 females, aged 17-58 years) had congestive heart failure without coronary artery disease, familial cardiomyopathy, rheumatic fever