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为了解周围神经损伤后的修复过程，观察了大鼠坐骨神经冷冻损伤当时至 ４ 周后的超微结构。发现冷冻损伤后３ 天，除变性神经纤维外，尚有新生轴突，皆由雪旺细胞包裹着。１ 周后新生神经纤维已较丰富，以无髓纤维为多，有髓纤维罕见，且髓鞘较薄，雪旺细胞和巨噬细胞皆吞噬变性的神经纤维。此后，形态正常的雪旺细胞和神经纤维渐多，被吞噬的变性物质渐少，直至损伤 ４ 周后，神经组织恢复到基本正常，但仍可见少量被吞噬的髓样结构。这提示，冷冻引起的周围神经损伤，３ 天后开始再生，１ 周后出现有髓神经纤维，４ 周后基本完成修复过程。
To understand the repair process of peripheral nerve injury, we observed the ultrastructural changes of rat sciatic nerve from 4 weeks after injury. Three days after the injury was found, there were neonatal axons in addition to degenerative nerve fibers, both of which were surrounded by Schwann cells. After 1 week, the newborn nerve fibers have been more abundant, with no myelinated fibers, rare myelinated fibers, and myelin thinner. Both Schwann cells and macrophages are phagocytic degenerative nerve fibers. Since then, normal morphology of Schwann cells and nerve fibers gradually increased, phagocytic degeneration of less, until 4 weeks after injury, the nerve tissue returned to normal, but still see a small amount of phagocytic myeloid structure. This suggested that peripheral nerve injury caused by freezing, 3 days after the start of regeneration, 1 week after the occurrence of myelinated nerve fibers, 4 weeks after the completion of the repair process.