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目的 :探讨鼻咽癌骨转移患者骨显像的特点及临床应用价值。方法 :选择 45 0例鼻咽癌患者行全身骨核素显像。结果 :45 0例鼻咽癌中发现颈淋巴结转移占 71 1% ( 32 0 45 0 ) ,骨转移占 6 3 8% ( 2 87 45 0 )。 415例低分化或未分化鳞状细胞癌骨显像阳性率为 6 6 0 % ( 2 74 415 ) ,35例高分化鳞状细胞癌的骨显像阳性率 37 1% ( 13 415 ) ,两者比较差异有显著意义 (P <0 0 0 1)。骨转移的部位以脊柱为多见 ,其余依次为胸部、骨盆、肢体和颅骨。结论 :鼻咽癌易发生骨转移 ,核素全身骨显像对于临床诊断分期及治疗有一定的意义 ,可作为鼻咽癌诊断的常规检查
Objective: To investigate the characteristics and clinical value of bone imaging in nasopharyngeal carcinoma patients with bone metastases. Methods: Forty-five patients with nasopharyngeal carcinoma underwent whole body radionuclide imaging. Results: Of the 45 cases of nasopharyngeal carcinoma, cervical lymph node metastasis was found to be 71.1% (32 0 45 0) and bone metastasis was 63.8% (2 87 45 0). The positive rate of bone imaging in 415 cases of poorly differentiated or undifferentiated squamous cell carcinoma was 66.0% (2 74 415). The positive rate of bone imaging in 35 cases of well differentiated squamous cell carcinoma was 37.1% (13 415) The difference was significant (P <0.01). The site of bone metastasis is more common in the spine, followed by the chest, pelvis, limbs and skull. Conclusion: Bone metastasis of nasopharyngeal carcinoma is easy to occur and the whole body radionuclide imaging has certain significance for the clinical diagnosis and treatment of stage, and can be used as a routine examination for the diagnosis of nasopharyngeal carcinoma