论文部分内容阅读
目的 观察 2 4例复发性鼻咽癌的自发与放疗后凋亡及分裂指数。方法 每一病例均观察放疗前和复发后的病理切片 ,光镜下计数凋亡指数和分裂指数。结果 结果表明 ,鼻咽癌的自发凋亡指数为 0 .5 5 % ,分裂指数为 0 .36 %。放疗后复发时凋亡指数为 0 .6 3% ,分裂指数为 0 .40 %。结论 与其它肿瘤相比 ,鼻咽癌属于低凋亡指数肿瘤 ,复发时凋亡指数和分裂指数与治疗前相比无明显差别。凋亡指数在鼻咽癌预后因素中的作用尚需进一步研究。
Objective To observe the spontaneous and post-radiotherapy apoptosis and mitotic index in 24 cases of recurrent nasopharyngeal carcinoma. Methods The pathological sections before and after radiotherapy were observed in each case. The apoptotic index and mitotic index were counted under light microscope. The results showed that the spontaneous apoptosis index of nasopharyngeal carcinoma was 0.55%, the dividing index was 0.36%. After radiotherapy, the apoptotic index was 0.636% and the cleavage index was 0.40%. Conclusion Compared with other tumors, nasopharyngeal carcinoma belongs to the low apoptosis index tumor, the recurrence of apoptosis index and mitotic index compared with before treatment no significant difference. The role of apoptosis index in the prognosis of nasopharyngeal carcinoma needs further study.