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目的探讨结直肠系膜全切术对结直肠癌患者的生存质量的影响,为临床应用结直肠系膜全切术提供依据。方法 200例行手术治疗的结直肠癌患者为研究对象,随机分为A、B两组,其中A组120例患者行结直肠系膜全切术,B组80例患者未行结直肠系膜全切术,对比两组患者术后生存率及生存质量。结果 A组3年存活率明显高于B组,差异有统计学意义(P<0.01),A组1年复发率、性功能障碍率和排尿功能障碍率明显低于B组,差异有统计学意义(P<0.01),两组排便功能障碍率比较,差异无统计学意义(P>0.05)。结论结直肠癌患者行结直肠系膜全切术后的存活率及生存质量明显优于未行结直肠系膜全切术的患者,可考虑作为符合条件的结直肠癌患者首选治疗方法。
Objective To investigate the effect of total mesorectal excision on the quality of life in patients with colorectal cancer and provide evidence for clinical application of total mesorectal excision. Methods A total of 200 patients with colorectal cancer undergoing surgical treatment were randomly divided into A and B groups. 120 patients in group A underwent total mesorectal excision, and 80 patients in group B were not subjected to complete mesorectal excision The postoperative survival rate and quality of life of the two groups were compared. Results The 3-year survival rate in group A was significantly higher than that in group B (P <0.01). The 1-year recurrence rate, sexual dysfunction rate and voiding dysfunction rate in group A were significantly lower than those in group B (P <0.01). There was no significant difference in defecation dysfunction rate between the two groups (P> 0.05). Conclusions The survival rate and quality of life of patients with colorectal cancer after colorectal mesorectal excision are significantly better than those without colorectal mesorectal excision and may be considered as the first choice of treatment for patients with colorectal cancer.