Schilder病是一种脑白质广泛脱髓鞘疾病,临床上比较罕见,经脑组织活检证实的病例国内尚未见报道。该病表现可以类似其他多种疾病,如颅内肿瘤、脑炎、代谢性疾病等,容易误诊,需做脑组织病理检查确诊。 患者,男,8岁。1991年9月出现精神不振,学习成绩下降,孤僻。11月听力明显减退,12月左侧肢体无力,跛行。1992年1月双眼视力下降,3月不能看字学 Schilder disease is a broad demyelinating disease of white matter, relatively rare in clinical practice, confirmed by brain biopsy cases have not been reported in China. The performance of the disease can be similar to a variety of other diseases, such as intracranial tumors, encephalitis, metabolic diseases, etc., easily misdiagnosed, need to do brain histopathology confirmed. Patient, male, 8 years old. In September 1991 there was a lack of energy, academic performance decline, withdrawn. Hearing decreased significantly in November, left limb weakness in December, limp. January 1992 binocular vision loss, in March can not read word learning