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角膜接触镜及保存液有被棘阿米巴污染的危险。目前棘阿米巴角膜炎尚无有效的治疗方法且预后较差。作者应用新型广谱抗霉菌药物itraconazole口服和双氯苯咪唑(miconazole)滴眼联合手术清创治愈3例棘阿米巴角膜炎。本文报告3例(男1,女2),配戴软性角膜接触镜矫正近视。例1曾用自制盐水消毒接触镜并在戴镜过夜一个月后发现该眼充血和异物感、例2、例3在摘去接触镜后发现一眼与例1有相同的症状,检查还发现角膜知觉减退。3例先后2次就医经抗生素及抗病毒、激
Contact lenses and preservatives have the risk of being contaminated with Acanthamoeba. Acanthamoeba keratitis is currently no effective treatment and the prognosis is poor. The authors apply a new broad spectrum anti-fungal drug itraconazole orally and miconazole combined with debridement surgery cured Acanthamoeba keratitis in 3 cases. This article reports 3 cases (male 1, female 2), wearing soft contact lenses to correct myopia. Example 1 was used homemade salt water disinfection contact lens and wear a mirror one month after the night was found congestion and foreign body sensation, Example 2, Example 3 Remove the contact lens and found in Example 1 has the same symptoms, examination also found that the cornea Perception diminished. 3 cases have 2 times medical treatment by antibiotics and antivirus, shock