应用巢式聚台酶链反应（ＰＣＲ）技术检测了１８例乙型肝炎（乙肝）患者石蜡包埋心、肝组织中的ＨＢＶＤＮＡ，并与其免疫组化及原位杂交结果作了比较。二组引物检测的结果表明：在肝组织中均有ＨＢＶ感染，其中５例有ＨＢＶ复制。心肌组织ＨＢＶＤＮＡ的检出率为５５．６％，不存在ＨＢＶ的复制。心脏病理检查可见一些非特异性改变，如脂变、水肿和纤维素样坏死等。病理变化与心电图、临床症状、体征及ＰＣＲ检测结果无相关件。以上结果提示：乙肝患者心脏出现的一些病变可能是由于沉积于心肌内的免疫复合物介导损伤的结果。 Nested polymerase chain reaction (PCR) was used to detect HBVDNA in 18 paraffin-embedded and hepatic tissues of patients with hepatitis B (hepatitis B) and compared with the results of immunohistochemistry and in situ hybridization. Two sets of primers test results showed that: all have HBV infection in liver tissue, of which 5 cases of HBV replication. Myocardial tissue HBVDNA detection rate was 55.6%, there is no replication of HBV. Cardiac pathology shows some non-specific changes, such as lipid changes, edema and fibrinoid necrosis. Pathological changes and ECG, clinical symptoms, signs and PCR test results without correlation. The above results suggest that some lesions in the heart of hepatitis B patients may be the result of immune complex-mediated damage deposition in the myocardium.