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目的探究针对溃疡性结肠炎疾病采用美沙拉嗪结合中药灌肠治疗的临床效果。方法 2010年6月~2013年广州市荔湾区人民医院进行治疗的60例溃疡性结肠炎患者进随机均分为观察组和对照组(n=30)。观察组患者给予美沙拉嗪1.5 g/次结合中药灌肠进行治疗,中药采用苦参、白术、黄连各20 g、紫菜根、白头翁、西草根以及黄柏各15 g,6 g诃子10 g仙鹤草。经过水煎后量取200 mL药汁于睡前进行灌肠处理。对照组患者给予单纯美沙拉嗪药物1.5 g/次进行治疗。比较2组患者治疗效果及不良反应发生情况。结果治疗后,观察组患者7 d内病症改善情况以及治疗后30 d内有效率均明显优于对照组,2组比较差异有统计学意义。结论针对溃疡性结肠炎疾病给予美沙拉嗪结合中药灌肠进行治疗,患者症状得到很好改善,病情复发情况少,总体治疗效果比较满意。
Objective To investigate the clinical efficacy of mesalazine combined with traditional Chinese medicine enema in the treatment of ulcerative colitis. Methods Sixty patients with ulcerative colitis who were treated in Liwan District People’s Hospital of Guangzhou from June 2010 to 2013 were randomly divided into observation group and control group (n = 30). The observation group was given Mesalazine 1.5 g / time combined with Chinese medicine enema for treatment, Chinese medicine using Sophora, Atractylodes, Coptis 20 g each, seaweed root, Pulsatilla, savannah and cork each 15 g, 6 g Myrobalan 10 g Agrimony . After decoction measure 200 mL concoction enema at bedtime. Patients in the control group were treated with pure mesalazine 1.5 g / time. The treatment effect and adverse reactions in two groups were compared. Results After treatment, the patients in the observation group improved their symptoms within 7 days and the effective rates within 30 days after treatment were significantly better than those in the control group. The difference between the two groups was statistically significant. Conclusion The treatment of ulcerative colitis with mesalazine combined with traditional Chinese medicine enema has shown that the symptoms of the patients are well improved, the recurrence of the disease is less, and the overall treatment effect is satisfactory.