在动物实验中,细胞分裂的发生与牙齿移动的生物学有关。因此,本研究的目的是在使用正畸矫治器的前和后,测量人牙龈沟中的肿瘤坏死因子-α(TNF)的改变。研究对象是20位患者的50颗采用正畸力移动的牙齿。为了在牙龈沟中重复获得TNF,将表面涂有单克隆抗体的顺磁珠(5μm)放入这50颗牙齿的牙龈 In animal experiments, cell division occurs with the biology of tooth movement. Therefore, the purpose of this study was to measure the changes of tumor necrosis factor-alpha (TNF) in human gingival sulcus before and after using the orthodontic appliance. The subjects were 50 teeth of 20 patients who moved orthodontically. In order to repeatedly obtain TNF in the gingival sulcus, paramagnetic beads (5 [mu] m) coated with a monoclonal antibody were placed in the gums of these 50 teeth