近来,宿主防御在莱姆病发病机制中的作用引起了临床医生和研究者的极大兴趣。疏螺旋体感染者临床表现的多样性表明针对免疫系统各种成分的反应不同,且不足以在早期控制感染。为更好地理解蜱咬后病原和免疫系统的相互作用,需要回答下述的几个重要问题。第一个问题是感染微生物的特性。临床流行病 Recently, the role of host defense in the pathogenesis of Lyme disease has drawn great interest from clinicians and researchers. The diversity of clinical manifestations of Borrelia shows that the responses to various components of the immune system are different and not sufficient to control the infection early. In order to better understand the interactions between tick bites and the immune system, several important questions need to be answered. The first problem is the nature of the infected microorganisms. Clinical epidemics