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目的对梧州市的HIV感染长期不进展病例进行流行病学描述性分析,以了解HIV感染长期不进展病例的流行病学分布特点。方法从艾滋病综合防治信息系统中筛选出感染时间至少5年以上、现住址为梧州市的HIV感染存活病例、并且从未接受过抗逆转录病毒治疗、CD4检测结果从未低于410 cells/μL的病例,进行年龄、性别、感染途径、接受随访及CD4检测等情况的流行病学描述性分析。结果根据以上述条件筛选,在2 956例存活的感染者及病人中共筛选出72例HIV感染长期不进展病例,占2.44%(72/2 956)。其中男性57例,女性15例。30~49岁年龄段的54例,占该年龄段存活病例的3.10%(54/1 743)。经注射吸毒途径感染的38例,占该途径感染的存活病例5.03%(38/755)。有工作的41例,占有工作的存活病例1.88%(41/2 181)。除诊断年限为10年组的病例接受随访的次数平均不足每年1次外,其余诊断年限组的病例每年接受1次以上的随访;所有的病例每年或每两年接受一次CD4检测。结论根据本次分析结果,应该加强规范化的随访干预,提供更多的健康教育宣传,对特征人群采用更行之有效的干预措施,使其更加关心自身的健康,积极面对社会,更好的保护和促进身体免疫功能。
Objective To carry out epidemiological descriptive analysis of long-term non-progression of HIV infection in Wuzhou City in order to understand the epidemiological distribution of long-term non-progression of HIV infection. Methods The HIV-infected survivors who had been infected for at least 5 years and lived in Wuzhou City were screened out from HIV / AIDS prevention and control information system and never received antiretroviral therapy. CD4 test results never dropped below 410 cells / μL Of cases, for age, gender, route of infection, follow-up and CD4 testing and other epidemiological descriptive analysis. Results According to the above screening conditions, a total of 72 cases of long-term non-progression of HIV infection were screened among 2 956 surviving patients and patients, accounting for 2.44% (72/2 956). 57 males and 15 females. 54 patients aged 30 to 49 years, accounting for 3.10% (54/1 743) of the surviving cases in this age group. Thirty-eight cases were infected by injecting drug, accounting for 5.03% (38/755) of the surviving cases. 41 had work, and 1.88% (41/2 181) of the surviving occupations had jobs. The patients in the other diagnosis years received more than one follow-up each year except for the average number of follow-up visits of patients in the 10-year diagnosis group. All cases received CD4 test every year or every two years. Conclusion According to the results of this analysis, standardized follow-up interventions should be strengthened to provide more publicity on health education and adopt more effective interventions for the characteristic population to make them more concerned about their own health and actively face the society and better Protect and promote body’s immune function.