作者采用转移因子(TF)对36例Ⅱ期恶性黑素瘤患者进行了随机治疗。首先对所有患者进行手术治疗(姑息手术或根治术),然后进行胸部X线检查、肝脏和骨骼扫描、头颅CT检查、骨骼活检和淋巴管造影。如果结果均为阴性,则随机分配18例患者为TF治疗组;另18例为对照组,不再进行治疗。此后, The authors used transfer factor (TF) to treat 36 patients with stage II malignant melanoma at random. All patients were first surgically treated (palliative surgery or radical surgery), followed by chest X-ray examination, liver and bone scan, head CT examination, bone biopsy, and lymphangiography. If the results were negative, 18 patients were randomized to the TF treatment group; the other 18 were control subjects and no longer treated. After that,