根据一项新的研究,在用于基础研究或临床开发的140种人胚胎干细胞系当中,5种人胚胎干细胞系在肿瘤抑制基因TP53上获得突变。其中的两种人胚胎干细胞系H1和H9已用于人体中,不过还没有证据证实它们在受者体内导致癌症产生。相关研究结果在线发表在Nature期刊上,论文标题为“Human pluripotent stem cells recurrently acquire and expand dominant negative According to a new study, five human embryonic stem cell lines acquired mutations in the tumor suppressor gene TP53 among 140 human embryonic stem cell lines used for basic research or clinical development. Two of these human embryonic stem cell lines, H1 and H9, have been used in humans, but there is no evidence that they cause cancer in the recipient. Relevant research results published online in Nature, the paper entitled ”Human pluripotent stem cells recurrently acquire and expand dominant negative