应用以氦代替氮的混合气体意味着一种新的治疗声门下狭窄的途径,即在不改变上气道直径而仅减低吸入气体密度情况下,降低部分梗阻气道的摩擦阻力并增加了吸入的混合气体的线性速度,其结果减轻了呼吸功。最近的一些研究报告了这种疗法在改善儿童及成人患上气道梗阻时的临床功效。Wolfson等证明,支气管肺发育不良的早产儿呼吸了氦-氧混合气而降低了肺阻力、呼吸阻力及呼吸的机械功率。他们认为 The use of a gas mixture of helium instead of nitrogen means a new approach to treating subglottic stenosis, which reduces the frictional resistance of partially obstructed airways and increases inhalation without changing the diameter of the upper airway and reducing the density of the inhaled gas only The linear velocity of the gas mixture reduces the work of breathing. Some recent studies have reported the clinical efficacy of this therapy in improving airway obstruction in children and adults. Wolfson et al. Demonstrated that bronchopulmonary dysplasia in premature infants breathed helium-oxygen mixture and decreased pulmonary resistance, respiratory resistance, and mechanical power of respiration. they think