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目的:探讨孕期甲状腺功能低下症(简称“甲低”)治疗对1岁内婴幼儿发育商(DQ)的影响。方法:选择110例妊娠合并“甲低”并自愿配合治疗的患者为研究组,同期100例无妊娠合并症、并发症的孕妇为对照组,回顾性分析其相关临床资料。对所有1岁内的婴幼儿DQ进行监测,并作对比分析。结果:妊娠合并“甲低”积极治疗患者婴幼儿DQ与正常孕妇所生婴幼儿DQ比较,差异无统计学意义(P>0.05);两组儿童总DQ分级评价结果比较,差异无统计学意义(P>0.05);孕妇“甲低”治疗时间越早婴幼儿DQ越高,治疗开始在妊娠5个月前与5个月后比较,差异有统计学意义(P<0.05)。结论:孕早期甲低筛查并积极治疗完全可以将甲状腺功能低下对婴幼儿DQ的影响降低,孕妇甲状腺功能低下治疗时间越早婴幼儿DQ越高。
Objective: To investigate the effect of hypothyroidism during pregnancy on infants and toddlers (DQ) within 1 year of age. Methods: A total of 110 pregnant women with pregnancy complicated with hypothyroidism were selected as the study group. 100 pregnant women with no complications of pregnancy and complications during the same period were selected as the control group. The clinical data were retrospectively analyzed. All 1-year-old infants and young children DQ monitoring, and for comparative analysis. Results: There was no significant difference in DQ between infants and toddlers infants born in pregnant women with active treatment of pregnancy and normal children (P> 0.05). There was no statistical difference between the two groups in total DQ grade evaluation (P 0. 05). The earlier the treatment time of pregnant women and hypothyroidism was, the higher the DQ was in infants and young children. The treatment started 5 months before pregnancy and 5 months later, the difference was statistically significant (P0.05) . Conclusion: The detection of early hypothyroidism and aggressive treatment can reduce the impact of hypothyroidism on infant DQ. The earlier the hypothyroidism is, the higher the DQ in infants and young children.