用反相色谱法分析山莨菪碱、甲氧氯普胺、地塞米松及苯海拉明四种组份，在甲醇－水流动相体系中加入少许三乙胺使Ｃ１８固定相表面的化学活性改变，结合选择流动相的适宜ｐＨ值，达到了满意的色谱分离效果。ＵＶ检测，其线性范围分别为：１０～２４０ｍｇ／Ｌ、１０～２４０ｍｇ／Ｌ，１０～２００ｍｇ／Ｌ，以及１５～２００ｍｇ／Ｌ，最大Ｒｓ≤３９４。 Anisodamine, metoclopramide, dexamethasone and diphenhydramine were analyzed by reverse phase chromatography. A small amount of triethylamine was added to the methanol-water mobile phase to make the chemical activity of C18 stationary phase Change, combined with the appropriate choice of mobile phase pH, to achieve a satisfactory chromatographic separation. UV detection, the linear range of 10 ~ 240mg / L, 10 ~ 240mg / L, 10 ~ 200mg / L, and 15 ~ 200mg / L, the maximum Rs ≤ 3.94.