目的:探讨乳酸菌阴道胶囊在产后混合性阴道炎中的作用。方法:选取2010年12月～2011年12月来保定市妇幼保健院妇保科进行产后检查确诊为阴道炎的患者260例,对其进行阴道微生态检查(包括微生态参数:阴道菌群、清洁度、乳杆菌分级、PH值)以明确病原菌,对于混合感染的患者,将其随机分为两组,试验组:阴道用乳酸菌阴道胶囊2粒/次,连用10天。对照组:阴道用双唑泰栓1粒/次,连用10天。2周后两组进行随访,对其临床症状减轻情况、PH及阴道清洁度进行比较。结果:产后妇女病原体感染以加德纳杆菌为主,产后妇女阴道的混合感染率为42.69%(111/260),常见类型为细菌性阴道病(BV)+需氧菌性阴道炎(AV)占54.95%(61/111),用药前两组在临床症状(外阴瘙痒、白带增多异味、阴道灼痛等)、PH值、清洁度等方面比较差异无统计学意义(P>0.05)。用药后两组临床症状较治疗前均改善,但治疗组较对照组症状改善明显,差异有统计学意义(P<0.05);用药后两组阴道清洁度均较用药前升高,但治疗组高于对照组,差异有统计学意义(P<0.05);用药后两组PH均有降低,但用药后试验组低于对照组,差异有统计学意义(P<0.05)。结论:微生态检查是检出产后阴道混合感染非常重要的手段,产后应用乳酸菌阴道胶囊不仅可以抑制致病菌的繁殖和生长,还可显著改善阴道微环境,对于降低阴道感染机会具有重要作用。 Objective: To investigate the role of lactobacillus vaginal capsules in postpartum mixed vaginitis. Methods: Two hundred and ten patients with vaginitis confirmed by postpartum examination from December 2010 to December 2011 were selected for vaginal microbiological examination (including micro-ecological parameters: vaginal flora, cleaning Degree, Lactobacillus grade, PH value) to clear the pathogens, for mixed infection patients, they were randomly divided into two groups, the experimental group: vaginal lactic acid bacteria vaginal capsules 2 capsules / time, once every 10 days. Control group: vaginal double oxazole suppository 1 / times, once every 10 days. After 2 weeks, the two groups were followed up, their clinical symptoms, PH and vaginal cleanliness were compared. Results: The main pathogens of postpartum women were Gardnerella vaginalis. The mixed infection rate of postpartum women was 42.69% (111/260). Common types were bacterial vaginosis (BV) + aerobic vaginitis (AV) Accounting for 54.95% (61/111). There was no significant difference in clinical symptoms (genital pruritus, vaginal discharge increased vaginal odor, vaginal burning, etc.), PH value and cleanliness between the two groups before treatment (P> 0.05). After treatment, the clinical symptoms of both groups improved compared with those before treatment, but the symptoms in the treatment group were significantly improved compared with the control group (P <0.05). The vaginal cleanliness of both groups increased after treatment, but the treatment group The difference was statistically significant (P <0.05). The PH of both groups decreased after treatment, but the difference was statistically significant (P <0.05) in the experimental group after treatment. Conclusions: Microecological examination is a very important measure to detect postpartum vaginal mixed infection. Postpartum vaginal lactic acid bacteria capsule can not only inhibit the growth and reproduction of pathogens, but also improve the vaginal microenvironment remarkably, which plays an important role in reducing the chance of vaginal infection.