近十多年来,对肝昏迷的认识有了新进展,1975年 Fischer 等发现肝昏迷时血浆氨基酸失平衡的特征,提出枝链氨基酸(以下简称 BCAA)/芳香族氨基酸(以下简称 AAA)克分子比值的概念(以下简称 BCAA/AAA 比值),并首次用富含BCAA 的 FO80溶液治疗肝昏迷获得成功,为人们所重视。一、血浆氨基酸失平衡与肝昏迷的关系肝昏迷时血浆氨基酸图型异常改变大致可概括 In recent ten years, there has been new progress in the understanding of hepatic coma. In 1975, Fischer et al. Found the imbalance of plasma amino acids during hepatic coma, and proposed that branched chain amino acids (hereafter referred to as BCAA) / aromatic amino acids The concept of molecular ratio (hereinafter referred to as BCAA / AAA ratio), and for the first time with the BCAA-rich solution of FO80 hepatic coma is successful, as people pay attention. First, the relationship between plasma amino acid imbalance and hepatic coma Liver coma when the abnormal changes in plasma amino acid profile can be broadly summarized