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目的:探讨影响腹腔镜结肠癌根治术病人预后的危险因素以及术后并发症发生对病人生存时间的影响。方法:回顾性分析我院2006年5月至2010年5月行限期腹腔镜结肠癌根治术的病人339例,根据Dindo并发症评分系统对病人术后并发症进行分级。应用Kaplan-Meier法和COX回归分析影响病人预后的相关危险因素。结果:339例经腹腔镜结肠癌根治术病人的术后并发症发生率为24.8%(84/339)。单因素分析发现,ASA评分、手术时间、肿瘤最大直径、国际抗癌联盟(UICC)分期和Ⅱ级或以上并发症是影响病人预后的危险因素。其中,手术时间、肿瘤最大直径、UICC分期和Ⅱ级或以上并发症是影响病人预后的独立危险因素。结论:术后并发症发生可能对腹腔镜结肠癌根治术病人的预后产生不良影响。
Objective: To investigate the risk factors affecting the prognosis of patients undergoing laparoscopic radical resection of colon cancer and the impact of postoperative complications on the survival time of patients. Methods: A retrospective analysis of 339 cases undergoing laparoscopic radical mastectomy in our hospital from May 2006 to May 2010 was performed. The postoperative complications were graded according to the Dindo Complication Rating System. Kaplan-Meier method and COX regression analysis of the impact of the prognosis of patients with risk factors. Results: The incidence of postoperative complications in 339 patients undergoing radical resection of colon cancer was 24.8% (84/339). Univariate analysis found that ASA score, operation time, tumor diameter, UICC stage Ⅱ and grade Ⅱ or above complications were the risk factors affecting the prognosis of patients. Among them, the operation time, the maximum tumor diameter, UICC stage and grade Ⅱ or more complications are independent risk factors affecting the prognosis of patients. Conclusion: Postoperative complications may have an adverse effect on the prognosis of patients undergoing laparoscopic radical resection of colon cancer.