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Ｐｈ染色体为慢性粒细胞白血病（ＣＭＬ）的特异标记染色体，存在于９５％的ＣＭＬ患者中。近年来随着分子生物学的进展，已阐明Ｐｈ染色体所导致的ｂｃｒ／ａｂｌ基因重排是某些白血病发病的关键因素。本文复习了国内外有关文献，对该领域目前研究的进展做一简要综述
The Ph chromosome is a specific marker chromosome for chronic myeloid leukemia (CML) and is present in 95% of CML patients. In recent years, with the progress of molecular biology, it has been clarified that the rearrangement of bcr/abl gene caused by Ph chromosomes is a key factor in the pathogenesis of certain leukemias. This article reviews the literature at home and abroad and gives a brief overview of the current research progress in this field.