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采取脾脏植入法成功地建立了ＨＣＣ细胞实验性肝转移模型，将造模后２８只裸鼠随机分为中药组、化 疗组、中化组与对照组。中药组灌服肠癌康复汤，化疗组予５－ＦＵ与ＭＭＣ腹腔或鼠尾静脉注射，中化组在灌服 肠癌康复汤的同时，结合５－ＦＵ与ＭＭＣ腹腔或鼠尾静脉注射，对照组仅以生理盐水灌胃，以各组裸鼠一般生存 状态、血清ＣＥＡ含量、裸鼠肝转移率与肝转移程度为观察指标。结果显示，肠癌康复汤可延长荷瘤裸鼠的生存 期，改善在活状态，配合化疗可显著降低裸鼠血清 ＣＥＡ水平，抑制 ＨＣＣ细胞实验性肝转移的发生率与转移程 度。
The model of experimental hepatic metastasis of HCC cells was successfully established by spleen implantation. 28 nude mice were randomly divided into Chinese medicine group, chemotherapy group, Sinochem group and control group. The Chinese medicine group was fed with bowel cancer rejuvenation decoction and the chemotherapy group was given intravenous injection of 5-FU and MMC into the abdominal cavity or rat tail vein. The Zhonghua group was combined with 5-FU and MMC intraperitoneal or rat tail vein injection at the same time as the colon cancer rehabilitation soup. In the control group, only normal saline was used to gavage, and the general survival status, serum CEA content, liver metastasis rate and liver metastasis of the nude mice in each group were used as observation indexes. The results showed that the cancer rehabilitation soup can prolong the survival period of tumor-bearing nude mice and improve the living status. Combined with chemotherapy, it can significantly reduce serum CEA levels in nude mice and inhibit the incidence and degree of liver metastasis of HCC cells.