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目的:观察血液灌流串联血液透析对救治百草枯中毒患者的效果。方法:对照组采用常规急救方法,观察组在常规治疗基础上给予HP联合HD治疗。结果:观察组的总有效率(76.5%)明显高于对照组(38.5%),差异显著(P<0.01)。观察组相较于对照组的尿素氮(BUN)和血肌酐(Cr)显著下降,P<0.01。结论:在常规治疗下,采用HP联合HD能够有效清除血液中的百草枯,有利于纠正肺水肿,平稳机体内组织环境,预防器官衰竭,降低死亡率。
Objective: To observe the effect of hemoperfusion in series hemodialysis on paraquat poisoning patients. Methods: The control group was treated by conventional emergency method. The observation group was treated with HP combined with HD on the basis of routine treatment. Results: The total effective rate (76.5%) in the observation group was significantly higher than that in the control group (38.5%) (P <0.01). The levels of BUN and Cr in the observation group were significantly lower than those in the control group (P <0.01). Conclusion: Under the routine treatment, HP combined with HD can effectively remove paraquat in the blood, which is good for correcting pulmonary edema, stabilizing the tissue environment, preventing organ failure and reducing mortality.