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随着辅助生殖技术的发展,盆腔输卵管病变是体外受精-胚胎移植(in vitro fertilizationembryo transfer,IVF-ET)后异位妊娠(EP)发生的高危因素。超促排卵(COH)周期大量的外源性性激素导致子宫内膜发育与胚胎发育不同步,宫腔粘连、子宫内膜炎、子宫内膜息肉、疤痕子宫等不良的宫腔环境是导致IVF-ET后EP的危险因素,移植时间不同及新鲜胚胎还是冻融胚胎移植及移植后黄体支持与EP的发生是否有关报道不一。辅助孵化(AH)并不能显著改善患者的妊娠结局,反而会增加患者EP的发生率。EP的发生与移植技术有关,胚胎移植深度对EP可能有一定的影响。
With the development of assisted reproductive technology, pelvic fallopian tube disease is a high risk factor for ectopic pregnancy (EP) after in vitro fertilization embryo transfer (IVF-ET). Ovulation (COH) cycle a large number of exogenous sex hormones lead to endometrial development and embryonic development is not synchronized, intrauterine adhesions, endometritis, endometrial polyps, uterine and other uterine unfavorable uterine environment is leading to IVF- The risk factors of EP after ET, the time of transplantation, and whether the fresh embryo or frozen-thawed embryo transfer and post-transplant luteal support and the occurrence of EP are related to different reports. Assisted hatching (AH) does not significantly improve the outcome of patients with pregnancy, but will increase the incidence of EP patients. The occurrence of EP is related to the transplantation technique. The depth of embryo transfer may have some influence on EP.