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目的:分析2007-2009年南京地区抗感染药物应用状况及趋势,为临床合理应用抗感染药及其科学管理提供依据。方法:应用金额排序法和用药频度排序法,对南京地区23家医院2007-2009年临床使用的抗感染药物进行统计和分析。结果:2007-2009年抗感染药物用药总额增长迅速,到2010年为止,金额已过10亿元,年均增长率为22.38%,其中β内酰胺类药物占市场份额的一半以上。位于DDDs排序前列的为左氧氟沙星、罗红霉素和阿莫西林。结论:2007-2009年南京地区抗感染药物各品种使用基本规范,但仍应加强对于β内酰胺类、喹诺酮类药物及大环内酯类等药物的管理,以提高药物疗效,减少药物耐药性。
OBJECTIVE: To analyze the status and trends of anti-infectives application in Nanjing from 2007 to 2009 and provide evidences for rational use of anti-infectives and their scientific management. Methods: The amount of antimicrobial agents used in clinical practice in 23 hospitals in Nanjing area during 2007-2009 were analyzed and statistically analyzed by the method of order of amount and frequency of medication. Results: The total amount of anti-infective drugs increased rapidly in 2007-2009. By 2010, the total amount of anti-infective drugs had surpassed 1 billion yuan, with an average annual growth rate of 22.38%. Among them, β-lactam accounted for more than half of the market share. Among the top ranked DDDs are levofloxacin, roxithromycin, and amoxicillin. Conclusion: The basic norms of using anti-infective drugs in Nanjing area during 2007-2009 are basically used, but the management of drugs such as β-lactams, quinolones and macrolides should be strengthened so as to improve the curative effect and reduce the drug resistance Sex.