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目的探讨风湿性心瓣膜病并发体循环动脉栓塞的临床特征。方法收集并回顾性分析资料完整的风湿性心瓣膜病516例。结果风湿性心瓣膜病并发体循环动脉栓塞48例（占总分析病例的9．3％），主要见于二尖瓣狭窄合并心房颤动患者，其中脑动脉栓塞25例（52％）、髂动脉合并股动脉栓塞8例（16．7％）、股动脉栓塞10例（20.8％）、肠系膜动脉栓塞4例（8．3％）、肾动脉栓塞1例（2％）。结论体循环动脉栓塞在风湿性心瓣膜病中并非少见，对于二尖瓣狭窄合并有心房颤动者应长期抗凝治疗。
Objective To investigate the clinical characteristics of rheumatic heart valve disease complicated with systemic arterial embolism. Methods A total of 516 cases of rheumatic valvulopathy were collected and retrospectively analyzed. Results 48 cases of rheumatic heart valve disease complicated by systemic arterial embolism (9.3% of the total analysis cases), mainly seen in patients with mitral stenosis and atrial fibrillation, including cerebral arterial embolism in 25 cases (52%), iliac artery combined with stock 8 cases (16.7%) had arterial embolism, 10 cases (20.8%) had femoral artery embolization, 4 cases (8.3%) had mesenteric artery embolization and 1 case (2%) had renal artery embolization. CONCLUSIONS: Circulating arterial embolism is not uncommon in rheumatic valvular disease and should be treated with long-term anticoagulation for patients with mitral stenosis and atrial fibrillation.