【摘 要】
：
Valid animal models are useful for studying the pathophysiology of specific disorders,such as neural disease,diabetes and cancer.Previous molecular phylogeny st
【机 构】
：
Key Laboratory of Systems Biology,Institute of Biochemistry and Cell Biology,Shanghai Institutes for
论文部分内容阅读
Valid animal models are useful for studying the pathophysiology of specific disorders,such as neural disease,diabetes and cancer.Previous molecular phylogeny studies indicate that the tree shrew is in the same order as (or a close sister to) primates,and thus may be an ideal model in which to study human disease.In this study,the proteome of liver and muscle tissue in tree the shrew was identified by combining peptide fractionation and LC-MS/MS identification.In total,2146 proteins were detected,including 1759 proteins in liver samples and 885 proteins in skeletal muscle samples from the tree shrew.Further sub-source analysis revealed that nearly half of the identified proteins (846 proteins and 418 proteins) were derived from human database.In this study,we are the first to describe the characteristics of the proteome from the liver and skeletal muscle of the tree shrew.Phylogenetic tree analysis based on these proteomic data showed that the tree shrew is closer to primates (human) than to glires (the mouse and rat).
其他文献
The human serum proteome is closely associated with the state of the body.Endogenous peptides derived from proteolytic enzymes cleaving on serum proteins are wi
以特征价格理论为基础,采用组合模型的形式建立了中山市商品住宅用地特征价格模型,并通过求偏导的方法测算了不同土地特征属性的边际土地增值量。结果表明:城市中心距、公共
１月９～１２日 学会秘书长封金芳出席北京大学成人教育学院在江苏省宜兴市召开的函授工作会议。会议主要议题：①布置函授站评估事宜；②布置１９９６年函授毕业生毕业工作；③商讨１９９６年招收函授生工
Caenorhabditis elegans hid-1 gene was first identified in a screen for mutants with a high-temperature-induced dauer formation (Hid) phenotype. Despite the fact
本试验以10年生、20年生库尔勒香梨为材料，研究不同施肥量处理、不同果实负载量条件下，对不同树龄库尔勒香梨叶绿体超微结构、光合特性等的影响。施肥量分为对照30kg/株、50kg/
Protein phosphorylation is a ubiquitous protein post-translational modification,which plays an important role in cellular signaling systems underlying vari
Parkinson’s disease is the second most common neurodegenerative disease in the world.Beta-arrestin-2 has been reported to be an important protein involved in D
今年七月前后，中国图书馆学会和大陆各省、市、自治区的图书馆学会，都将纪念自身成立的二十周年，肯定将发表一系文章来谈论此事。总结过去，展望未来，是世纪之交的普遍做法，图书馆界
轮台白杏(Armeniaca vulgaris cv. Luntaibaixing)是原产于新疆南疆盆地轮台县境内古老的地方优良品种,为制干、鲜食和开口杏核加工兼用品种。因其抗寒、抗旱、耐盐碱等优良