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目的探讨胰激肽原酶穴位注射对以蛋白尿为主的慢性肾小球肾炎的临床应用效果。方法将150例慢性肾小球肾炎患者随机分为对照组74例与治疗组76例,对照组采用常规药物治疗,治疗组在此基础上加用胰激肽原酶穴位注射治疗,观察两组患者24h蛋白水平及各项指标情况。结果果治疗组患者总有效率88.15%,显著高于对照组的74.32%,且治疗组SCr、BUN、血β2微球蛋白水平显著优于对照组,以上指标与对照组比较差异有统计学意义(P<0.05)。结论穴位注射胰激肽原酶可有效控制慢性肾炎患者蛋白尿水平,该法简单易行,无毒副作用,值得在临床广泛推广应用。
Objective To investigate the clinical effect of pancreatic kallikrein (AKI) injection on proteinuria-based chronic glomerulonephritis. Methods A total of 150 patients with chronic glomerulonephritis were randomly divided into control group (n = 74) and treatment group (n = 76). The control group was treated with conventional drugs. The treatment group was treated with pancreatic kallikrein acupuncture point injection. Two groups Patients with 24h protein levels and various indicators. Results The total effective rate of the treatment group was 88.15%, which was significantly higher than that of the control group (74.32%), and the levels of SCr, BUN and β2 microglobulin in the treatment group were significantly better than those in the control group. The above indexes were significantly different from the control group (P <0.05). Conclusion Acupoint injection of pancreatic kininogenase can effectively control proteinuria in patients with chronic nephritis, the method is simple, non-toxic side effects, it is widely used in clinical practice.