2006年5月19日,国家药品不良反应监测中心发布第22期《药品不良反应信息通报》,提醒医疗机构医护人员和药品生产经营企业,警惕左氧氟沙星注射剂和双黄连注射剂的严重不良反应/事件,尤其是过敏反应。在国家药品不良反应监测中心病例报告数据库中,左氧氟沙星注射剂的严重不良反应/事件以全身性损害、中枢及外周神经系统损害等为主,其中过敏反应问题较为典型。双黄连注射剂的严重不良反应/事件以全 On May 19, 2006, the National Center for Adverse Drug Reaction Monitoring released the 22nd “Information Bulletin on Adverse Drug Reactions” to remind medical and healthcare personnel and pharmaceutical production and operation enterprises to guard against the serious adverse reactions / events of levofloxacin and shuanghuanglian injection, Especially allergic reactions. In the national ADR surveillance center case report database, the serious adverse reactions / events of levofloxacin injection were generalized injury, central and peripheral nervous system damage, etc., among which the allergic reaction was typical. Shuanghuanglian injection of serious adverse reactions / events to the whole