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目的:比较一维、二维CT和容积测量三种方法测量肝转移介入治疗的效果．方法:22例肝转移的患者,在介入治疗前和术后3 mo行螺旋CT扫描．在CT工作站分别按一维和二维测量横断层面的全部病灶．用容积测量技术去追踪测量每个病灶,将每个病灶的总和归类于全效、部分有效、病变进展、病变稳定．结果:在22例肝转移介入治疗前后一维与二维测量符合率达95．5％(21／22),但容积测量8例与一维测量不符,6例与二例测量不符．4例一维和二维测量结果均为部分有效,而容积测量结果为病变稳定．2例一维和二维测量病变稳定者,容积测量则为部分有效．甚至有2例一维、二维测量为病变进展者,容积测量仍为病变稳定．结论:在肝转移瘤介入治疗前后,肿瘤容积测量结果在大多数患者与一维、二维测量结果不一致．若要证实容积测量的优势,还需要大样本的临床对照研究．
OBJECTIVE: To compare the effects of one-dimensional and two-dimensional computed tomography (CT) and volumetric measurements on interventional therapy of liver metastases. Methods: Twenty-two patients with liver metastases underwent helical CT scan before intervention and 3 mo after operation. All lesions were transected in one and two dimensions at the CT workstation, respectively. Volumetric measurements are used to track each lesion, and the sum of each lesion is classified as fully effective, partially effective, the lesion progresses and the lesion is stable. Results: The coincidence rate of one-dimensional and two-dimensional measurement was 95.5% (21/22) before and after the interventional treatment of 22 cases of hepatic metastases, but the volume measurement did not accord with the one-dimensional measurement in 8 cases and the other 6 cases did not. 4 cases of one-dimensional and two-dimensional measurement results are partially effective, and volume measurement results for the disease stable. Two cases of one-dimensional and two-dimensional measurement of lesion stability, the volume measurement is partially effective. There are even two cases of one-dimensional and two-dimensional measurement of disease progression, volume measurement is still stable. Conclusion: The measurement of tumor volume before and after interventional therapy of liver metastases is inconsistent with one-dimensional and two-dimensional measurement in most patients. To demonstrate the advantages of volumetric measurements, large controlled clinical studies are also needed.