论文部分内容阅读
世界各国,在肿瘤免疫治疗中,生物佐剂卡介苗占很重要的地位,它对吞噬细胞系统有强烈的激活作用,其抗肿瘤效应与此有关。卡介苗对急性白血病、恶性黑色素瘤都有一定疗效,目前还正在试用于其他肿瘤。卡介苗系活菌菌苗,大量使用有一定的副作用,如局部发红、硬结、溃疡、淋巴结肿痛等,有时还能引起全身反应,如恶寒、发热、无力等。另外,在使用中还有一不便之处,容易失效,保存困难。
In various countries of the world, the biological adjuvant BCG represents an important position in tumor immunotherapy. It has a strong activation effect on the phagocyte system, and its anti-tumor effect is related to this. BCG has a certain effect on acute leukemia and malignant melanoma, and is currently being tested on other tumors. BCG is a live bacterin vaccine that has a number of side effects, such as local redness, induration, ulcers, and lymphadenopathy. It can sometimes cause systemic reactions such as chills, fever, and weakness. In addition, there is an inconvenience in use, it is easy to fail, and it is difficult to save.