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目的:探讨标准通道经皮肾镜取石术(PCNL)在慢性肾功能不全患者中应用的安全性及有效性。方法:回顾性分析2005年12月～2010年11月行PCNL手术治疗的慢性肾功能不全病例,共92例患者,146次手术,统计手术效果并比较围手术期血肌酐水平、血色素、红细胞压积的变化。结果:一期手术清石率46.7%,总清石率64.1%,出血、术后发热、结石残留是主要并发症;术后与术前比较,血红蛋白、红细胞压积明显降低,具有统计学意义;血肌酐水平无显著性变化。结论:对于慢性肾功能不全患者,标准通道PCNL是安全有效的,手术对肾功能的近期影响不明显。
Objective: To investigate the safety and efficacy of standard percutaneous nephrolithotomy (PCNL) in patients with chronic renal failure. Methods: A retrospective analysis of patients with chronic renal failure undergoing PCNL surgery from December 2005 to November 2010 was performed. A total of 92 patients underwent 146 surgeries. The effects of perioperative serum creatinine, hemoglobin, hematocrit Product changes. Results: The rate of clear stone was 46.7%, the total clear stone was 64.1%, the bleeding, postoperative fever and residual stones were the main complications. The postoperative hemoglobin and hematocrit decreased significantly compared with those before operation, with statistical significance ; Serum creatinine levels did not change significantly. CONCLUSIONS: Standard access is safe and effective for patients with chronic renal insufficiency. The short-term impact of surgery on renal function is insignificant.