论文部分内容阅读
目的分析氟喹诺酮类药物临床应用中不良反应发生的情况,为临床合理用药提供信息。方法对121例氟喹诺酮类药物不良反应(ADR)报告进行回顾性分析。结果 121例不良反应发生涉及7种氟喹诺酮类药物,以左氧氟沙星和加替沙星最多。不良反应发生情况多表现为神经系统、消化系统及皮肤过敏反应。结论本类药物抗菌活性强,不良反应发生率较高。关注其治疗作用的同时,应重视其不良反应,以提高临床用药安全性和有效性。
Objective To analyze the occurrence of adverse reactions in the clinical application of fluoroquinolones and provide information for clinical rational drug use. Methods 121 cases of fluoroquinolone adverse drug reactions (ADR) report were retrospectively analyzed. Results The 121 adverse reactions involved seven fluoroquinolones, with the most levofloxacin and gatifloxacin. Adverse reactions occurred mostly in the nervous system, digestive system and skin allergies. Conclusion The antibacterial activity of these drugs is strong, the incidence of adverse reactions higher. At the same time of paying attention to its therapeutic effect, it should pay attention to its adverse reactions to improve the safety and effectiveness of clinical medication.