论文部分内容阅读
目的探讨原发性高血压患者动态血压和血压变异性与心肌做功指数的相关性。方法选择2014年6月至2015年5月河北医科大学附属以岭医院就诊的100例首诊高血压患者,根据心肌做功(Tei)指数中位数分为≤0.45为A组(51例),>0.45为B组(49例),采用单因素及多因素分析两组超声心动图、动态血压及血压变异性指标。结果B组LVESD、IVS、LVPW高于A组,B组Em低于A组,差异均有统计学意义(P<0.05)。B组24h SBP、24h DBP、d SBP、d DBP、n DBP高于A组,差异均有统计学意义(P<0.05),B组24h SCV、d SCV、n SCV、d DCV高于A组,差异均有统计学意义(P<0.05)。采用多元线性回归分析,结果显示,24h DBP、24h SCV、LVPW、Em是高血压患者Tei指数独立相关因素(P<0.05)。结论动态血压24h DBP升高、血压变异性24h SCV升高及左心室重构与Tei指数升高有关。
Objective To investigate the correlation between ambulatory blood pressure and variability of blood pressure and myocardial work index in patients with essential hypertension. Methods From January 2014 to May 2015, 100 cases of newly diagnosed hypertensive patients attending Yiling Hospital of Hebei Medical University were divided into group A (51 cases) ≤0.45 according to the median of myocardial work (Tei) index, > 0.45 for the B group (49 cases), univariate and multivariate analysis of echocardiography, ambulatory blood pressure and blood pressure variability indicators. Results The LVESD, IVS and LVPW in group B were significantly higher than those in group A, and the values of Em in group B were lower than those in group A (P <0.05). The 24h SBP, 24h DBP, d SBP, d DBP and n DBP in group B were higher than those in group A (P <0.05). The SCV, d SCV, n SCV and d DCV in group B were higher than those in group A , The differences were statistically significant (P <0.05). Multivariate linear regression analysis showed that 24h DBP, 24h SCV, LVPW and Em were independent correlative factors of Tei index in hypertensive patients (P <0.05). Conclusions The increase of ambulatory blood pressure (24h DBP), the increase of variability of blood pressure (24h SCV) and the remodeling of left ventricle are associated with the increase of Tei index.