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米索前列醇为人工合成的PGE类似物,它与米非司酮配伍终止早孕已在全世界广泛推广运用。近年来国内外文献报道用于晚期妊娠、促宫颈成熟和引产,与催产素比较具有成本低、简便、有效,缩短产程的特点。但给药途径、间隔时间及药量各家报道不一。为了解米索前列醇在晚妊引产中的有效性及安全性,我院采用阴道米索前列醇25ug引产进行临床观察,现将结果报告如下:
Misoprostol is a synthetic PGE analog, which combined with mifepristone termination of early pregnancy has been widely used throughout the world. In recent years, domestic and foreign literature reports for late pregnancy, cervical ripening and induction of labor, compared with oxytocin low cost, simple, effective, shorten the process of production. However, the route of administration, interval time and dose vary from one report to another. In order to understand the effectiveness and safety of misoprostol in late pregnancy induced labor, our hospital vaginal misoprostol 25ug induction of labor for clinical observation, the results are reported as follows: