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目的:观察并探讨左氧氟沙星治疗耐多药肺结核的临床疗效分析。方法:选取2014年7月~2015年11月来我院治疗的100例局肺结核患者进行回顾性分析,随机分成两组,即观察组与对照组。对照组患者采取临床常规药物治疗(对氨基水杨酸异烟肼、丙硫异烟胺片、利福喷丁、乙胺丁醇),观察组患者在对照组基础上增加左氧氟沙星进行治疗,观察两组患者在经过各自治疗后的临床疗效及不良反应。结果:两组患者在治疗3、6、12月后,经比较得知,观察组患者在痰菌阴转率方面明显优于对照组,两组患者的临床疗效比存在显著差异(P<0.05),具有统计学意义。结论:采取左氧氟沙星治疗耐多药肺结核其临床疗效可靠,疗效高、不良反应少,有利病变部位吸收及痰菌阴转,值得加大临床的推广及应用。
Objective: To observe and explore the clinical efficacy of levofloxacin in the treatment of multidrug-resistant pulmonary tuberculosis. Methods: A total of 100 cases of pulmonary tuberculosis patients treated in our hospital from July 2014 to November 2015 were retrospectively analyzed and randomly divided into two groups: the observation group and the control group. Patients in the control group were treated with routine drug treatment (isoniazid, propylthiouracil tablets, rifapentine, ethambutol). Patients in the observation group were treated with levofloxacin on the basis of the control group, and observed Two groups of patients after their respective clinical efficacy and adverse reactions. Results: After 3, 6, and 12 months of treatment, compared with the control group, the observation group was significantly better than the control group in sputum negative conversion rate, the clinical efficacy of the two groups were significantly different (P <0.05 ),has statistical significane. Conclusion: The levofloxacin treatment of multidrug-resistant pulmonary tuberculosis with reliable clinical efficacy, high efficacy, fewer adverse reactions, beneficial absorption of the affected area and sputum negative conversion, it is worth to increase the clinical promotion and application.