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目的分析奥美拉唑治疗胃溃疡合并出血的临床价值。方法对2011年1月-2013年1月于我院治疗的80例胃溃疡合并出血患者随机分为观察组与对照组,各40例,分别在对症综合治疗的基础上采用奥美拉唑和法莫替丁治疗。观察两组患者治疗显效率、总有效率、HP转阴率及药物不良反应率。结果观察组患者治疗总有效率及HP转阴率均显著高于对照组(P<0.05),差异具有统计学意义,而治疗显效率与药物不良反应率无显著性差异(P>0.05)。结论奥美拉唑用于治疗胃溃疡合并出血安全性好,治疗有效率高,值得临床推广。
Objective To analyze the clinical value of omeprazole in the treatment of gastric ulcer combined with bleeding. Methods Eighty patients with gastric ulcer combined with hemorrhage treated in our hospital from January 2011 to January 2013 were randomly divided into observation group and control group, 40 cases in each group. On the basis of comprehensive treatment of symptomatic patients, omeprazole and Famotidine treatment. The two groups of patients were observed markedly effective, total effective rate, HP negative rate and adverse drug reaction rate. Results The total effective rate and the negative conversion rate of HP in the observation group were significantly higher than those in the control group (P <0.05), and the difference was statistically significant. However, there was no significant difference between the effective rate of treatment and the adverse drug reaction rate (P> 0.05). Conclusion Omeprazole for the treatment of gastric ulcer combined with bleeding is safe, effective treatment, worthy of clinical promotion.