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以洋地黄及/或利尿剂联合治疗慢性心力衰竭的疗效颇不理想。近年来经补充血管扩张剂联合治疗后,则常可奏效。AR—L_(115)的结构〔2-(2-methory-4-methylsulfinyl-phenyl)-Imidazo(4.5 B)-Pysidine〕和洋地黄或儿茶酚胺并无相似之处,但对心脏亦有正性肌力作用。本文报道 AR-L_(115)治疗顽固性心力衰竭时的血液动力学效应。
The combination of digitalis and / or diuretics in the treatment of chronic heart failure is not ideal. In recent years by the combination of vasodilators after treatment, often can be effective. The structure of AR-L_ (115) [2- (2-methory-4-methylsulfinyl-phenyl) -Imidazo (4.5 B) -Pysidine〕 and digitalis or catecholamines no similarities, but the heart also has positive inotropic effect. This article reports the hemodynamic effects of AR-L_ (115) treatment of refractory heart failure.