在产生免疫力的小鼠体内寄生的伯氏疟原虫(K 173株)转变为一种变异型,它增强对抗体的抵抗力并对成熟红细胞的侵入增加;在正常小鼠体内培育时,这种变异型又可转变为正常型。进一步的研究显示这种变异型的疟原虫趋嗜多色性红细胞的特性显著减少,导致潜伏期增殖缓慢,对成熟红细胞的侵 Plasmodium berghei (strain K 173) parasitized in immunocompetent mice transforms into a variant that increases resistance to antibodies and increases invasion of mature erythrocytes; when grown in normal mice, this Variation can be transformed into normal type. Further studies have shown that this variant of Plasmodium polyketide erythrocytes trait significantly reduced the characteristics, resulting in slow proliferation of the incubation period, the invasion of mature erythrocytes