八十年代初,随着准分子激光器研制的发展,各国学者从193nm准分子激光能精确蚀刻多聚化合物得到启发,开始研究此波长激光与生物组织的相互作用。Srinvasan与Lane分别用皮肤、肌肉、牙齿、角膜等生物样品试验,发现光量子为6.4eV的紫外激光与生物组织作用时,主要是光化学作用(Photochemical mechanism),受照区域周围热损伤轻微。深入的研究表明:适当控制激光的各种物理参数(脉冲重复频率、单脉冲的能量及照射时间),就可对生物样品进行光分解(Photodecomposition)及光解切除(Photoablation)。七十年代以 In the early 1980s, with the development of excimer lasers, scholars from all over the world were inspired by 193nm excimer laser to accurately etch the poly-compound, and began to study the interaction between this wavelength laser and biological tissues. Srinvasan and Lane, respectively, with skin, muscle, teeth, cornea and other biological samples tested and found that 6.4eV photons of ultraviolet laser and biological tissue role, the main photochemical mechanism (Photochemical mechanism), thermal damage around the irradiated area slightly. In-depth studies have shown that photodecomposition and photoablation of biological samples can be performed by properly controlling various laser physical parameters (pulse repetition frequency, single-pulse energy and irradiation time). Seventies