The Hexi Corridor is the northmost foreland basin of the Tibetan Plateau and its formation is controlled by the northern marginal fault of Tibet, Altyn Tagh Fault (ATF)-North Qilian Shan marginal Fault (NQF), and the southern Kuantan Shan-Longshou Shan Fault (KLF). So its study is important to understanding the mechanism of Tibet formation and its influence on global climate change. The oldest Cenozoic sediments in the Corridor is the Huoshaogou Formation which consists of terrigenous fine conglomerate, sandstone, sandy mudstone and mudstone, depositing in al-luvial to lacustrine and fan delta sedimentary environments. Detailed paleomagnetic measurements of this sequence at Yumen clearly reveal eleven pairs of normal and reversed polarities. Fossil mammals found around the section support that most of the observed polarities can be well correlated with chrons between 13n and 18r of the standard geomag-netic polarity time scale, yielding ages of 40.2-33.35 Ma. The mean declinations of this sequence and its immediately above stratigraphy indicate an 18.3° rapid clockwise rotation of the Hexi Corridor. Since this sequence has been strongly folded and is capped by an angular unconformity, we think that the presence of the thick alluvial fan conglomeration at the bottom of the foreland basin may indicate the initial de-formation and uplift of the northern Qilian Shan. This proc-ess could occur at latest at 40.2 Ma, driven by the faults NQF and KLF that thrust onto the Hexi corridor respectively from its southern and northern margins. These faults are in an early response to the collision of India with Asia, while the unconformable termination and rotation of the Huoshaogou Formation at ~33.35 Ma indicate other early episode of rapid tectonic deformation and uplift of the northern Tibet. The Hexi Corridor is the northmost foreland basin of the Tibetan Plateau and its formation is controlled by the northern marginal fault of Tibet, Altyn Tagh Fault (ATF) - North Qilian Shan marginal Fault (NQF), and the southern Kuantan Shan-Longshou Shan Fault (KLF). So its study is important to understand the mechanism of Tibet formation and its influence on global climate change. The oldest Cenozoic sediments in the Corridor is the Huoshaogou Formation which consists of terrigenous fine conglomerate, sandstone, sandy mudstone and mudstone, depositing in al-luvial to lacustrine and fan delta sedimentary environments. Detailed paleomagnetic measurements of this sequence at Yumen clearly reveal eleven pairs of normal polar reversed polar. Fossil mammals found around the section support that most of the observed polarities can be well correlated with chrons between 13n and 18r of the standard geomag-netic polarity time scale, yielding ages of 40.2-33.35 Ma. The mean declinations of t his sequence and its immediately following stratigraphy indicate an 18.3 ° rapid clockwise rotation of the Hexi Corridor. we think that the presence of the thick alluvial fan conglomeration at the bottom of the foreland basin may indicate the initial de-formation and uplift of the northern Qilian Shan. This procedure-up could occur at latest at 40.2 Ma, driven by the faults NQF and KLF that thrust onto the Hexi corridor respectively from its southern and northern margins. These faults are in an early response to the collision of India with Asia, while the unconformable termination and rotation of the Huoshaogou Formation at ~ 33.35 Ma indicate other early episode of rapid tectonic deformation and uplift of the northern Tibet.