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目的:探讨2型糖尿病患者胰腺的多排螺旋计算机断层扫描(CT)灌注的临床价值。方法:选择2015年7月至2016年7月南阳市第一人民医院收治的75例2型糖尿病患者作为观察组,并选择70例健康者为对照组,观察两组胰腺灌注结果、比较观察组不同病程灌注结果以及观察组不同病程各部位径线长。结果:观察组胰腺头、体、尾部达峰时间(TTP)、表面通透性(PS)及平均通过时间(MTT)值均显著高于对照组,差异具有统计学意义(P<0.05),观察组不同部位血流量(BF)、血流容积(BV)值与对照组相比低,差异具有统计学意义(P<0.05);观察组病程10年及以上胰腺头、体、尾部TTP、PS、MTT头、体部值与病程10年以内相比较高,差异具有统计学意义(P<0.05),BF、BV值病程10年及以上较病程10年以内低,差异具有统计学意义(P<0.05),MTT尾部值两组比较,差异无统计学意义(P>0.05)。结论:多排螺旋CT灌注检查能够较为准确、客观检测2型糖尿病患者胰腺情况,可为糖尿病临床诊断治疗提供可靠参考依据。
Objective: To investigate the clinical value of multislice spiral computed tomography (CT) perfusion in type 2 diabetic patients. Methods: From July 2015 to July 2016, 75 cases of type 2 diabetes mellitus admitted to First People’s Hospital of Nanyang City were selected as observation group and 70 healthy persons as control group. The results of pancreas perfusion were observed and compared between observation group Different course of perfusion results as well as observation group of different parts of the path length of each line. Results: The time to peak (TTP), the surface permeability (PS) and mean transit time (MTT) in the head, tail and body of the observation group were significantly higher than those in the control group, with statistical significance (P <0.05) The BF and BV values in different parts of the observation group were lower than those in the control group (P <0.05). The TTP, (P <0.05). The durations of BF and BV were lower than those within 10 years (P <0.05), and the differences were statistically significant (P < P <0.05). There was no significant difference in MTT tail value between the two groups (P> 0.05). Conclusion: Multi-slice spiral CT perfusion examination can be more accurate and objective detection of pancreatic status in patients with type 2 diabetes, which can provide a reliable reference for the clinical diagnosis and treatment of diabetes mellitus.