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目的观察M胆碱能受体阻滞剂与β受体激动剂在临床哮喘病症治疗中的应用与效果。方法抽选我院于2012年2月~2014年3月收治的88例哮喘患者作为观察对象,随机将其分成甲乙两组各44例,分别给予其噻托溴铵与噻托溴铵+沙丁胺醇药物应用,并对其治疗效果进行观察。结果甲组治疗总有效率为77.27%,乙组的治疗总有效率为90.91%,两组比较,差异显著(P<0.05)。同时,用药后,两组患者的肺功能均有所改善,且以乙组的改善程度更为显著(P<0.05)。结论针对临床上哮喘患者的实际情况,给予其M胆碱能受体阻断剂与β受体激动剂联合应用,可明显患者缓解的喘息症状,改善患者的肺功能,总体效果显著,值得临床大力推广。
Objective To observe the application and effect of M cholinergic receptor blockers and β receptor agonists in the treatment of clinical asthma disorders. Methods A total of 88 patients with asthma who were admitted to our hospital from February 2012 to March 2014 were randomly divided into two groups, 44 patients in each group. The patients were given tiotropium bromide and tiotropium bromide plus salbutamol Drug application, and the treatment effect was observed. Results The total effective rate of treatment group A was 77.27%, and the total effective rate of treatment group B was 90.91%. There was significant difference between the two groups (P <0.05). At the same time, the lung function of both groups improved after treatment, and the improvement of group B was more significant (P <0.05). Conclusion According to the actual situation of patients with clinical asthma, given its M cholinergic receptor blockers and β-agonists in combination, can significantly alleviate the symptoms of wheezing and improve lung function in patients with a significant overall effect, it is worth clinical Promote.