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目的应用有创-无创序贯机械通气治疗AECOPD合并严重呼吸衰竭的临床疗效观察。方法选择ICU患者60例,分为序贯组32例及有对照组28例,观察两组患者有创通气时间、总机械通气时间、住ICU时间、治愈好转率、呼吸机相关性肺炎患病率、再插管率及死亡率。结果序贯组各项观察指标显著优于对照组,差异有统计学意义。结论序贯机械通气治疗AECOPD并严重呼吸衰竭安全有效,优于传统有创机械通气方法。
Objective To evaluate the clinical efficacy of invasive and noninvasive sequential mechanical ventilation in the treatment of AECOPD complicated with severe respiratory failure. Methods Sixty ICU patients were divided into two groups: sequential group (n = 32) and control group (n = 28). The durations of invasive ventilation, total mechanical ventilation, ICU stay, healing improvement and ventilator-associated pneumonia Rate, re-intubation rate and mortality. Results Sequential group of various indicators was significantly better than the control group, the difference was statistically significant. Conclusions Sequential mechanical ventilation is safe and effective in the treatment of AECOPD and severe respiratory failure, which is superior to the traditional invasive mechanical ventilation.