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对43例因癌瘤疼痛的患首进行一项回顾性研究,观察鞘内注射类鸦片药物疗法对不同性质疼痛(特别是神经病理性和伤害感受性疼痛)的镇痛效果。 神经病理性疼痛(neuropathic pain)系指肿瘤浸润至预臂、腰骶神经丛或周围神经及脊髓受压所引起的疼痛。伤害感受性疼痛(nociceptive pain)系指肿瘤浸润至头颅、内脏器官和(或)血官引起的疼痛。 根据临床和影像学资料,将患者疼痛按性质分为伤害感受性(23例)和神经病理性(20例)。伤害感受性者平均疗程为5个月,而神经病理性者仅为2.5个月。应用鞘内类鸦片药物疗法后,伤害感受性患者最初有77.8％疼痛中度缓
A retrospective study of 43 patients with cancer pain was performed to observe the analgesic effect of intrathecal injection of opioid therapy on different types of pain, in particular neuropathic and nociceptive pain. Neuropathic pain refers to pain caused by infiltration of the tumor into the forearm, lumbosacral plexus or peripheral nerve and spinal cord. Nociceptive pain refers to the pain caused by tumor infiltration into the head, internal organs and / or blood. According to the clinical and imaging data, the patients were divided into nociceptive (n = 23) and neuropathological (n = 20) by nature. The average duration of nociception was 5 months, compared to only 2.5 months for neuropathic individuals. After intrathecal opioid therapy, nociceptive patients initially had moderate pain with 77.8% pain