大白鼠正常心电图100例分析

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有关大白鼠正常心电图资料报道较少,且各作者之结果差异颇大。鉴于目前大白鼠在实验室中应用日益广泛,常将心电图作为筛选和观察实验效果的一项重要指标。为此,我们选用我校动物所繁殖之健康成年大鼠100只,其中雄鼠75只,雌鼠25只,体重248±44克,在乙醚轻度麻醉下,取仰卧位,用热笔式直接描记型心电图机记录6个肢导和一个单报中央胸导的心电图。纸速50毫米/秒,定标电压1毫伏=20毫米。各导均用短针电极刺入皮下,肢导电极安放部位与人相同,胸导刺入动物心搏最强点处皮下(胸骨左缘第5肋间距中线约1厘米处)。100例正常心电图资料经统计、分析后小结如下:一、大白鼠正常心电图各成分之正常值及特点:100例均为窦性心律,心律齐,心率为370~500次/分,均值为418±34次/分。P 波在aVR 和aVL 导联为负向,其他各导均为正向,各导P 波电压间差异较大,而时间除aVL 和V 导外均相近,均值为0.0173±0.0043秒。 There are few reports on the normal ECG data of rats, and the results vary greatly among authors. In view of the present rats are widely used in the laboratory, ECG as a screening and observation often an important indicator of experimental results. To this end, we use 100 healthy adult rats breeding our school animals, of which 75 male rats, 25 females, weight 248 ± 44 grams, under mild ether anesthesia, supine position with hot pen Direct-record type electrocardiogram machine records 6 limbs and a single central chest ECG report. Paper speed 50 mm / s, calibration voltage 1 mV = 20 mm. Each lead was stabbed into the skin with a short needle electrode, and the limb lead was placed in the same position as the human body. The thoracic guide pierced the strongest point of the animal’s skin at the strongest point (the fifth rib of the left margin of the sternum was about 1 cm away from the midline). 100 cases of normal ECG data by statistics, the analysis is as follows: First, the normal ECG of rats normal components and characteristics: 100 cases were sinus rhythm, heart rate Qi, heart rate 370 to 500 beats / min, mean 418 ± 34 beats / min. P wave in aVR and aVL lead is negative, the other leads are positive, each P wave voltage difference between the larger, and the time except aVL and V are similar to the guide, with an average of 0.0173 ± 0.0043 seconds.
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