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目的了解北京市各唐氏综合征筛查机构工作现况及存在问题,更好地规范北京市唐氏综合征筛查工作方法。方法采用描述性统计学方法分析北京市唐氏综合征筛查机构实验室的管理、检测方法、检测设备、工作量及质控情况进行分析。结果 61家唐氏综合征筛查机构中使用孕中期三联筛查方法者占72.13%;按照卫生部行业标准的要求开展室内质控者占42.62%,室内质控合格率与该机构年筛查样本量及筛查频度均有一定关系;全市筛查实验室筛查的高风险率参差不齐,最高的为12.64%,最低的为0。结论统一北京市各机构筛查方法及方案,并按照人群需求对实验室进行合理布局,减少唐氏综合征筛查实验室数量,提高血生化筛查质量。
Objective To understand the status quo and existing problems of all Down’s syndrome screening institutions in Beijing and to better standardize the screening methods for Down’s syndrome in Beijing. Methods Descriptive statistics were used to analyze the management, testing methods, testing equipment, workload and quality control of Down’s syndrome screening laboratory in Beijing. Results 61 pregnant women with Down’s syndrome screening triple screening method accounted for 72.13%; in accordance with the requirements of the Ministry of Health industry standards for indoor quality control who accounted for 42.62%, indoor quality control pass rate and the agency’s annual screening The sample size and the frequency of screening are related to each other. The high-risk screening rate of screening screening laboratories across the city is uneven, with the highest being 12.64% and the lowest being 0. Conclusion The method and scheme of screening various institutions in Beijing are unified, and the reasonable layout of laboratories according to the needs of the population, reducing the number of Down’s syndrome screening laboratories, and improving the quality of blood biochemical screening.